RA/SRA (Contract), Immunology

Here at Tizona Therapeutics, we value Patients First!
With this goal in mind, Tizona develops next-generation immunotherapies.
 
The successful development of immunotherapies represents one of the most important and exciting breakthroughs in cancer. Despite the recent progress in the field of immuno-oncology, existing immunotherapies are only effective in a relatively small number of patients and types of cancer – a limitation that we hope to overcome.  
 
Tizona’s therapies are designed to modulate the activity of immunosuppressive cells by targeting the cell types and biological mechanisms responsible for immune suppression in the tumor microenvironment. 
 
 

General Position Overview:

We are seeking a Research Associate or Sr. Research Associate to join the Immuno-oncology team at Tizona.  This role will support the development of our preclinical target pipeline and help characterize potential novel targets for Tizona.

 

Key Accountabilities/Core Job Responsibilities:

  • Develop and execute in vitro and ex vivo assays to assess mechanism of action of early-stage targets and novel immunotherapy agents
  • Provide critical lab support and work in a collaborative cross-functional team to design, execute and troubleshoot experiments
  • Generate, interpret, and present data to team
  • Willingness to learn and adopt new experimental skills as needed

 

Qualifications:

  • Experience with one or more of the following is strongly preferred:
    • In vitro functional assays using primary human immune cells (e.g., MLR, T-cell proliferation, suppression assays, macrophage polarization/differentiation, etc.); experience with myeloid cell-based assays is a plus
    • Experience with cytokine analysis (ELISA, MSD, Intracellular cytokine staining, etc.)
    • Experience with cell culture of established cell lines and isolation of primary immune cells from PBMCs
    • Skilled in immune assay development, establishment, and troubleshooting
  • Experience with mice and murine tumor models is a plus
  • Maintain detailed record of experiments and results. Experience with electronic lab notebook is a plus.
  • Highly motivated, independent, and creative individual with excellent communication and interpersonal skills.
  • Effective at working in a highly collaborative environment.
  • Strong leadership skills, self-motivated, adaptable to a dynamic environment.
  • Computer skills including proficiency in the use of Microsoft Word, Excel, and PowerPoint

 

Education and Experience Requirements:

  • B.S. or M.S. degree with 2+ years of biotechnology or pharmaceutical industry experience in cancer immunotherapy discovery and development.

 

 
Tizona Therapeutics is an Equal Opportunity Employer. We value diversity and are committed to providing employees a workplace free of discrimination and harassment. All employment decisions are based on qualifications, merit and business needs.

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