Join Our Team

Scientist

Here at Tizona Therapeutics, we value Patients First!
With this goal in mind, Tizona develops next-generation immunotherapies. 

The successful development of immunotherapies represents one of the most important and exciting breakthroughs in cancer. Despite the recent progress in the field of immuno-oncology, existing immunotherapies are only effective in a relatively small number of patients and types of cancer – a limitation that we hope to overcome.

Tizona’s therapies are designed to modulate the activity of immunosuppressive cells by targeting the cell types and biological mechanisms responsible for immune suppression in the tumor microenvironment.

 

General Position Overview:

Tizona Therapeutics is seeking for a highly motivated researcher to join the Antibody Development and Engineering team at Tizona. This role will support antibody discovery and optimization to generate new pipeline candidates using molecular biology and phage display. Additional activities include antibody screening, antibody characterization and mammalian cell culture.

 

Key Accountabilities/Core Job Responsibilities:   

  • Prior hands-on experience with antibody selection and screening using phage display for antibody discovery and optimization
  • Work cross-functionally to conduct antibody discovery, engineering, and lead optimization campaigns
  • Independently design, execute, analyze, and summarize experiments to characterize the binding of novel antibodies
  • Sub-clone Fabs and scFvs into desired isotypes and formats.
  • Mammalian cell transfection stable cell line generation, and characterization.
  • Excellent communication and ability to work both independently and in a team environment
  • Maintain detailed, timely, and complete records
  • Accomplish goals within project timelines

 

Education and Experience Requirements: 

  • Minimum Bachelor’s with + 5 years or a master’s with 3 years in molecular biology, biochemistry, or related field
  • Deep experience in molecular biology –construct design, site-directed mutagenesis, PCR, cloning, sequencing, and plasmid purification
  • Experience with techniques such as ELISA, FACS, Western Blot
  • Highly motivated, innovation-focused, independent individual
  • Highly collaborative and effective with multi-tasking
  • Excellent communication skills
  • Thrives in a fast paced and dynamic team environment, fast learning and adaptable
  • Proficiency with software for DNA sequence/vector analysis, graphical data analysis, FACS plots, for example: Geneious prime, Sequencher, GraphPad Prism, FlowJo


Tizona Therapeutics is an Equal Opportunity Employer. We value diversity and are committed to providing employees a workplace free of discrimination and harassment. All employment decisions are based on qualifications, merit and business needs.

Apply for this Position